Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate.
This paper is a cross-sectional study of spontaneous benign prostatic hyperplasia (BPH) in a single canine species. The effects of aging and hormonal changes in growth, histology and function of the prostate gland secretion of dogs studied in 42 male beagle dogs aged between 8 mo to 9 yrs. Beagle enlarged prostate for at least 6 years, whether normal or hyperplastic. In contrast, prostate secretory function , determined Rabbit Serum by the volume of ejaculate and total protein ejaculation, decreased sharply after 4 years of age. growth and functional changes in the prostate reciprocal closely associated with a progressive increase in the incidence of BPH, which is already evident in some dogs at the age of two. By the age of simple decline in serum androgen levels with no apparent change in serum 17 beta-estradiol levels. This indicates that the growth and functional changes associated with the development of BPH and begins very early in life change reflects the sensitivity...